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Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours
BACKGROUND: Neuroblastoma (NB) is a paediatric tumour of the sympathetic nervous system. Half of all cases are defined high-risk with an overall survival less than 40% at 5 years from diagnosis. The lack of in vitro models able to recapitulate the intrinsic heterogeneity of primary NB tumours has hi...
Autores principales: | Fusco, P., Parisatto, B., Rampazzo, E., Persano, L., Frasson, C., Di Meglio, A., Leslz, A., Santoro, L., Cafferata, B., Zin, A., Cimetta, E., Basso, G., Esposito, M. R., Tonini, G. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802324/ https://www.ncbi.nlm.nih.gov/pubmed/31638925 http://dx.doi.org/10.1186/s12885-019-6149-4 |
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