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Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract

BACKGROUND: Metabolic reprogramming is one of the hallmarks of cancer which favours rapid energy production, biosynthetic capabilities and therapy resistance. In our previous study, we showed bitter melon extract (BME) prevents carcinogen induced mouse oral cancer. RNA sequence analysis from mouse t...

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Detalles Bibliográficos
Autores principales: Sur, Subhayan, Nakanishi, Hiroshi, Flaveny, Colin, Ippolito, Joseph E., McHowat, Jane, Ford, David A., Ray, Ratna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802351/
https://www.ncbi.nlm.nih.gov/pubmed/31638999
http://dx.doi.org/10.1186/s12964-019-0447-y

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