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Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract
BACKGROUND: Metabolic reprogramming is one of the hallmarks of cancer which favours rapid energy production, biosynthetic capabilities and therapy resistance. In our previous study, we showed bitter melon extract (BME) prevents carcinogen induced mouse oral cancer. RNA sequence analysis from mouse t...
Autores principales: | Sur, Subhayan, Nakanishi, Hiroshi, Flaveny, Colin, Ippolito, Joseph E., McHowat, Jane, Ford, David A., Ray, Ratna B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802351/ https://www.ncbi.nlm.nih.gov/pubmed/31638999 http://dx.doi.org/10.1186/s12964-019-0447-y |
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