Cargando…

Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan

Tuberculosis (TB), caused by Mycobacterium tuberculosis bacteria, is a leading infectious cause of mortality worldwide, including in Pakistan. Drug resistant M. tuberculosis is an emerging threat for TB control, making it important to detect the underlying genetic mutations, and thereby inform treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jabbar, Abdul, Phelan, Jody E., de Sessions, Paola Florez, Khan, Taj Ali, Rahman, Hazir, Khan, Sadiq Noor, Cantillon, Daire M., Wildner, Leticia Muraro, Ali, Sajid, Campino, Susana, Waddell, Simon J., Clark, Taane G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802378/ https://www.ncbi.nlm.nih.gov/pubmed/31628383 http://dx.doi.org/10.1038/s41598-019-51562-6

Ejemplares similares

Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan
por: Napier, Gary, et al.
Publicado: (2022)

Prevalence of Multi-Drug Resistant Mycobacterium Tuberculosis in Khyber Pakhtunkhwa – A High Tuberculosis Endemic Area of Pakistan
por: ALI, SAJID, et al.
Publicado: (2020)

Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan
por: Khan, Anwar Sheed, et al.
Publicado: (2021)

Author Correction: Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan
por: Khan, Anwar Sheed, et al.
Publicado: (2021)

Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis
por: Wang, Linfeng, et al.
Publicado: (2023)

Large-scale genomic analysis of Mycobacterium tuberculosis reveals extent of target and compensatory mutations linked to multi-drug resistant tuberculosis
por: Napier, Gary, et al.
Publicado: (2023)

Search for Antimicrobial Activity Among Fifty-Two Natural and Synthetic Compounds Identifies Anthraquinone and Polyacetylene Classes That Inhibit Mycobacterium tuberculosis
por: Pollo, Luiz A. E., et al.
Publicado: (2021)

Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications
por: Gómez-González, Paula J, et al.
Publicado: (2022)

Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers
por: Libiseller-Egger, Julian, et al.
Publicado: (2020)

A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis
por: Deelder, Wouter, et al.
Publicado: (2022)

An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome
por: Gomez-Gonzalez, Paula J., et al.
Publicado: (2019)

TB-ML—a framework for comparing machine learning approaches to predict drug resistance of Mycobacterium tuberculosis
por: Libiseller-Egger, Julian, et al.
Publicado: (2023)

Spoligotyping analysis of Mycobacterium tuberculosis in Khyber Pakhtunkhwa area, Pakistan
por: Ali, Sajid, et al.
Publicado: (2019)

Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally
por: Phelan, Jody, et al.
Publicado: (2018)

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
por: Andreu, Nuria, et al.
Publicado: (2017)

Whole genome sequencing reveals large deletions and other loss of function mutations in Mycobacterium tuberculosis drug resistance genes
por: Gomes, Laura C., et al.
Publicado: (2021)

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies
por: Napier, Gary, et al.
Publicado: (2020)

Novel Mutations in MPT64 Secretory Protein of Mycobacterium tuberculosis Complex
por: Muhammad, Noor, et al.
Publicado: (2023)

Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data
por: Deelder, Wouter, et al.
Publicado: (2019)

Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data
por: Napier, Gary, et al.
Publicado: (2023)

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease
por: Phelan, Jody, et al.
Publicado: (2023)

Dissecting the Mycobacterium bovis BCG Response to Macrophage Infection to Help Prioritize Targets for Anti-Tuberculosis Drug and Vaccine Discovery
por: Medley, Jamie, et al.
Publicado: (2022)

Pre-Clinical Tools for Predicting Drug Efficacy in Treatment of Tuberculosis
por: Margaryan, Hasmik, et al.
Publicado: (2022)

Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis
por: Portelli, Stephanie, et al.
Publicado: (2018)

Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human host
por: Gómez-González, Paula Josefina, et al.
Publicado: (2023)

Using genomics to understand the origin and dispersion of multidrug and extensively drug resistant tuberculosis in Portugal
por: Perdigão, João, et al.
Publicado: (2020)

Structural and Genomic Insights Into Pyrazinamide Resistance in Mycobacterium tuberculosis Underlie Differences Between Ancient and Modern Lineages
por: Tunstall, Tanushree, et al.
Publicado: (2021)

A snapshot of translation in Mycobacterium tuberculosis during exponential growth and nutrient starvation revealed by ribosome profiling
por: Sawyer, Elizabeth B., et al.
Publicado: (2021)

Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan
por: khan, Muhammad Tahir, et al.
Publicado: (2019)

Large-scale reference-free analysis of flavivirus sequences in Aedes aegypti whole genome DNA sequencing data
por: Spadar, Anton, et al.
Publicado: (2023)

Methylation analysis of Klebsiella pneumoniae from Portuguese hospitals
por: Spadar, Anton, et al.
Publicado: (2021)

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania
por: Katale, Bugwesa Z., et al.
Publicado: (2020)

Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
por: Phelan, Jody, et al.
Publicado: (2016)

Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid
por: Gómez-González, Paula J., et al.
Publicado: (2021)

Comparison of GeneXpert MTB/RIF assay and LED-FM microscopy for the diagnosis of extra pulmonary tuberculosis in Khyber Pakhtunkhwa, Pakistan
por: Khan, Anwar Sheed, et al.
Publicado: (2018)

Mycobacterium tuberculosis whole genome sequencing provides insights into the Manila strain and drug-resistance mutations in the Philippines
por: Phelan, Jody E., et al.
Publicado: (2019)

Prediction of Multidrug-Resistant Tuberculosis Using Machine Learning Algorithms in SWAT, Pakistan
por: Ali, Mian Haider, et al.
Publicado: (2021)

SARS-CoV-2 Genome from the Khyber Pakhtunkhwa Province of Pakistan
por: Khan, Muhammad Tahir, et al.
Publicado: (2021)

Cystic echinococcosis: an emerging zoonosis in southern regions of Khyber Pakhtunkhwa, Pakistan
por: Khan, Shahid Niaz, et al.
Publicado: (2021)

Incidence of Multidrug-resistant Tuberculosis in Sindh, Pakistan
por: Khan, Rashid A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_v78nvfb1pvmv5dcro2iodbd1qu