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Secreted Rv1768 From RD14 of Mycobacterium tuberculosis Activates Macrophages and Induces a Strong IFN-γ-Releasing of CD4(+) T Cells

As the first line defensive mediators against Mycobacterium tuberculosis (M.tb) infection, macrophages can be modulated by M.tb to influence innate and adaptive immunity. Recently, we have identified several potential immunodominant T-cell antigens from the region of deletion (RD) of M.tb H37Rv, inc...

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Detalles Bibliográficos
Autores principales:	Yuan, Chun-Hui, Zhang, Simin, Xiang, Feiyan, Gong, Hongjian, Wang, Qian, Chen, Yan, Luo, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802416/ https://www.ncbi.nlm.nih.gov/pubmed/31681622 http://dx.doi.org/10.3389/fcimb.2019.00341

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