Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc

Intervertebral disc degeneration (IDD) is characterized by excessive apoptosis of nucleus pulposus (NP) cells and hyperactive extracellular matrix (ECM) catabolism. Our previous studies revealed the relationship between human islet amyloid polypeptide (hIAPP) and NP cell apoptosis. However, the role...

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Detalles Bibliográficos
Autores principales: Wu, Xinghuo, Liao, Zhiwei, Wang, Kun, Hua, Wenbin, Liu, Xianzhe, Song, Yu, Zhang, Yukun, Yang, Shuhua, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802624/
https://www.ncbi.nlm.nih.gov/pubmed/31554783
http://dx.doi.org/10.1038/s12276-019-0310-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802624/
https://www.ncbi.nlm.nih.gov/pubmed/31554783
http://dx.doi.org/10.1038/s12276-019-0310-7

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