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C-type natriuretic peptide attenuates renal osteodystrophy through inhibition of FGF-23/MAPK signaling

Renal osteodystrophy (ROD) occurs as early as chronic kidney disease (CKD) stage 2 and seems ubiquitous in almost all pediatric patients with CKD stage 5. Fibroblast growth factor (FGF)-23, a bone-derived endocrine regulator of phosphate homeostasis, is overexpressed in CKD and disturbs osteoblast d...

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Detalles Bibliográficos
Autores principales:	Zhang, Dong Dong, Wu, Yang Fang, Chen, Wei Xia, Xu, Yao, Liu, Si Yan, Luo, Huang Huang, Jiang, Guang Mei, Wu, Yue, Hu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802631/ https://www.ncbi.nlm.nih.gov/pubmed/31263178 http://dx.doi.org/10.1038/s12276-019-0265-8

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