Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

Type-2 Familial Partial Lipodystrophy is caused by LMNA mutations. Patients gradually lose subcutaneous fat from the limbs, while they accumulate adipose tissue in the face and neck. Several studies have demonstrated that autophagy is involved in the regulation of adipocyte differentiation and the m...

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Detalles Bibliográficos
Autores principales: Pellegrini, Camilla, Columbaro, Marta, Schena, Elisa, Prencipe, Sabino, Andrenacci, Davide, Iozzo, Patricia, Angela Guzzardi, Maria, Capanni, Cristina, Mattioli, Elisabetta, Loi, Manuela, Araujo-Vilar, David, Squarzoni, Stefano, Cinti, Saverio, Morselli, Paolo, Giorgetti, Assuero, Zanotti, Laura, Gambineri, Alessandra, Lattanzi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802660/
https://www.ncbi.nlm.nih.gov/pubmed/31375660
http://dx.doi.org/10.1038/s12276-019-0289-0

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