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Efficient exogenous DNA-free reprogramming with suicide gene vectors

Reprogramming with episomal vectors is an easy, safe, and cost-effective method to generate exogenous DNA-free (exogene-free) induced pluripotent stem cells (iPSCs). However, the genomic integration of exogenes is observed occasionally. Additionally, the removal of episomal DNA takes more than 70 da...

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Detalles Bibliográficos
Autores principales:	Lee, Minhyung, Ha, Jeongmin, Son, Ye Seul, Ahn, Hyunjun, Jung, Kwang Bo, Son, Mi-Young, Kim, Janghwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802735/ https://www.ncbi.nlm.nih.gov/pubmed/31324753 http://dx.doi.org/10.1038/s12276-019-0282-7

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