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MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy

PURPOSE: We investigated the impact on computed tomography (CT) image quality and photon, electron, and proton head‐and‐neck (H&N) radiotherapy (RT) dose calculations of three CT metal artifact reduction (MAR) approaches: A CT‐based algorithm (oMAR Philips Healthcare), manual water override, and...

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Autores principales: Nielsen, Jonathan Scharff, Van Leemput, Koen, Edmund, Jens Morgenthaler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802740/
https://www.ncbi.nlm.nih.gov/pubmed/31332792
http://dx.doi.org/10.1002/mp.13729
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author Nielsen, Jonathan Scharff
Van Leemput, Koen
Edmund, Jens Morgenthaler
author_facet Nielsen, Jonathan Scharff
Van Leemput, Koen
Edmund, Jens Morgenthaler
author_sort Nielsen, Jonathan Scharff
collection PubMed
description PURPOSE: We investigated the impact on computed tomography (CT) image quality and photon, electron, and proton head‐and‐neck (H&N) radiotherapy (RT) dose calculations of three CT metal artifact reduction (MAR) approaches: A CT‐based algorithm (oMAR Philips Healthcare), manual water override, and our recently presented, Magnetic Resonance (MR)‐based kerMAR algorithm. We considered the following three hypotheses: I: Manual water override improves MAR over the CT‐ and MR‐based alternatives; II: The automatic algorithms (oMAR and kerMAR) improve MAR over the uncorrected CT; III: kerMAR improves MAR over oMAR. METHODS: We included a veal shank phantom with/without six metal inserts and nine H&N RT patients with dental implants. We quantified the MAR capabilities by the reduction of outliers in the CT value distribution in regions of interest, and the change in particle range and photon depth at maximum dose. RESULTS: Water override provided apparent image improvements in the soft tissue region but insignificantly or negatively influenced the dose calculations. We however found significant improvements in image quality and particle range impact, compared to the uncorrected CT, when using oMAR and kerMAR. kerMAR in turn provided superior improvements in terms of high intensity streak suppression compared to oMAR, again with associated impacts on the particle range estimates. CONCLUSION: We found no benefits of the water override compared to the rest, and tentatively reject hypothesis I. We however found improvements in the automatic algorithms, and thus support for hypothesis II, and found the MR‐based kerMAR to improve upon oMAR, supporting hypothesis III.
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spelling pubmed-68027402019-11-20 MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy Nielsen, Jonathan Scharff Van Leemput, Koen Edmund, Jens Morgenthaler Med Phys THERAPEUTIC INTERVENTIONS PURPOSE: We investigated the impact on computed tomography (CT) image quality and photon, electron, and proton head‐and‐neck (H&N) radiotherapy (RT) dose calculations of three CT metal artifact reduction (MAR) approaches: A CT‐based algorithm (oMAR Philips Healthcare), manual water override, and our recently presented, Magnetic Resonance (MR)‐based kerMAR algorithm. We considered the following three hypotheses: I: Manual water override improves MAR over the CT‐ and MR‐based alternatives; II: The automatic algorithms (oMAR and kerMAR) improve MAR over the uncorrected CT; III: kerMAR improves MAR over oMAR. METHODS: We included a veal shank phantom with/without six metal inserts and nine H&N RT patients with dental implants. We quantified the MAR capabilities by the reduction of outliers in the CT value distribution in regions of interest, and the change in particle range and photon depth at maximum dose. RESULTS: Water override provided apparent image improvements in the soft tissue region but insignificantly or negatively influenced the dose calculations. We however found significant improvements in image quality and particle range impact, compared to the uncorrected CT, when using oMAR and kerMAR. kerMAR in turn provided superior improvements in terms of high intensity streak suppression compared to oMAR, again with associated impacts on the particle range estimates. CONCLUSION: We found no benefits of the water override compared to the rest, and tentatively reject hypothesis I. We however found improvements in the automatic algorithms, and thus support for hypothesis II, and found the MR‐based kerMAR to improve upon oMAR, supporting hypothesis III. John Wiley and Sons Inc. 2019-08-10 2019-10 /pmc/articles/PMC6802740/ /pubmed/31332792 http://dx.doi.org/10.1002/mp.13729 Text en © 2019 The Authors. Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle THERAPEUTIC INTERVENTIONS
Nielsen, Jonathan Scharff
Van Leemput, Koen
Edmund, Jens Morgenthaler
MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title_full MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title_fullStr MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title_full_unstemmed MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title_short MR‐based CT metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
title_sort mr‐based ct metal artifact reduction for head‐and‐neck photon, electron, and proton radiotherapy
topic THERAPEUTIC INTERVENTIONS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802740/
https://www.ncbi.nlm.nih.gov/pubmed/31332792
http://dx.doi.org/10.1002/mp.13729
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