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An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
The pathophysiology of osteoarthritis (OA) involves dysregulation of anabolic and catabolic processes associated with a broad panel of proteins that ultimately lead to cartilage degradation. An increased understanding about these protein interactions with systematic in vitro analyses may give new id...
Autores principales: | Neidlin, Michael, Chantzi, Efthymia, Macheras, George, Gustafsson, Mats G., Alexopoulos, Leonidas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802827/ https://www.ncbi.nlm.nih.gov/pubmed/31634377 http://dx.doi.org/10.1371/journal.pone.0224231 |
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