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Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol

INTRODUCTION: Nausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiem...

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Autores principales: Ho, Ka Yan, Lam, Katherine Ka Wai, Chung, Joyce Oi Kwan, Xia, Wei, Cheung, Ankie Tan, Ho, Long Kwan, Chiu, Sau Ying, Chan, Godfrey Chi Fung, LI, Ho Cheung William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803108/
https://www.ncbi.nlm.nih.gov/pubmed/31628132
http://dx.doi.org/10.1136/bmjopen-2019-031834
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author Ho, Ka Yan
Lam, Katherine Ka Wai
Chung, Joyce Oi Kwan
Xia, Wei
Cheung, Ankie Tan
Ho, Long Kwan
Chiu, Sau Ying
Chan, Godfrey Chi Fung
LI, Ho Cheung William
author_facet Ho, Ka Yan
Lam, Katherine Ka Wai
Chung, Joyce Oi Kwan
Xia, Wei
Cheung, Ankie Tan
Ho, Long Kwan
Chiu, Sau Ying
Chan, Godfrey Chi Fung
LI, Ho Cheung William
author_sort Ho, Ka Yan
collection PubMed
description INTRODUCTION: Nausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiemetics. There has been an exponential growth of studies to demonstrate the effectiveness of different complementary complementary medicine (CAM) to control nausea and vomiting during cancer treatment. Appropriate application of CAM enhances the effectiveness of antiemetics, thus reducing the symptom burden on children as well as improving their general condition and quality of life during cancer treatment. Nevertheless, it remains unclear which CAM is the best approach to help children to prevent or reduce nausea and vomiting during and after cancer treatment. This paper describes a protocol for identifying, analysing and synthesising research evidence on the effectiveness of CAM on nausea and vomiting in children with cancer. METHODS AND ANALYSIS: A total of 10 databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials which meet the inclusion criteria will be included. The primary outcome is the changes in nausea and vomiting either assessed by self-reported and/or objective measures. Review Manager 5.3 will be used to synthesise the data, calculate the treatment effects, perform any subgroup analysis and assess the risk of bias. ETHICAL AND DISSEMINATION: The results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required. PROSPERO REGISTRATION NUMBER: CRD42019135404.
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spelling pubmed-68031082019-10-31 Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol Ho, Ka Yan Lam, Katherine Ka Wai Chung, Joyce Oi Kwan Xia, Wei Cheung, Ankie Tan Ho, Long Kwan Chiu, Sau Ying Chan, Godfrey Chi Fung LI, Ho Cheung William BMJ Open Paediatrics INTRODUCTION: Nausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiemetics. There has been an exponential growth of studies to demonstrate the effectiveness of different complementary complementary medicine (CAM) to control nausea and vomiting during cancer treatment. Appropriate application of CAM enhances the effectiveness of antiemetics, thus reducing the symptom burden on children as well as improving their general condition and quality of life during cancer treatment. Nevertheless, it remains unclear which CAM is the best approach to help children to prevent or reduce nausea and vomiting during and after cancer treatment. This paper describes a protocol for identifying, analysing and synthesising research evidence on the effectiveness of CAM on nausea and vomiting in children with cancer. METHODS AND ANALYSIS: A total of 10 databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials which meet the inclusion criteria will be included. The primary outcome is the changes in nausea and vomiting either assessed by self-reported and/or objective measures. Review Manager 5.3 will be used to synthesise the data, calculate the treatment effects, perform any subgroup analysis and assess the risk of bias. ETHICAL AND DISSEMINATION: The results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required. PROSPERO REGISTRATION NUMBER: CRD42019135404. BMJ Publishing Group 2019-10-17 /pmc/articles/PMC6803108/ /pubmed/31628132 http://dx.doi.org/10.1136/bmjopen-2019-031834 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Paediatrics
Ho, Ka Yan
Lam, Katherine Ka Wai
Chung, Joyce Oi Kwan
Xia, Wei
Cheung, Ankie Tan
Ho, Long Kwan
Chiu, Sau Ying
Chan, Godfrey Chi Fung
LI, Ho Cheung William
Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title_full Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title_fullStr Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title_full_unstemmed Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title_short Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
title_sort systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol
topic Paediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803108/
https://www.ncbi.nlm.nih.gov/pubmed/31628132
http://dx.doi.org/10.1136/bmjopen-2019-031834
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