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Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice
Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10...
Autores principales: | Ellermann, Melissa, Gharaibeh, Raad Z., Fulbright, Laura, Dogan, Belgin, Moore, Lyndsey N., Broberg, Christopher A., Lopez, Lacey R., Rothemich, Aaron M., Herzog, Jeremy W., Rogala, Allison, Gordon, Ilyssa O., Rieder, Florian, Brouwer, Cory R., Simpson, Kenneth W., Jobin, Christian, Sartor, R. Balfour, Arthur, Janelle C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803345/ https://www.ncbi.nlm.nih.gov/pubmed/31481410 http://dx.doi.org/10.1128/IAI.00587-19 |
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