Cargando…

Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis

Chromatin remodeling complexes instruct cellular differentiation and lineage specific transcription. The BRG1/BRM-associated factor (BAF) complexes are important for several aspects of differentiation. We show that the catalytic subunit gene Brg1 has a specific role in cardiac precursors (CPs) to in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hota, Swetansu K., Johnson, Jeffrey R., Verschueren, Erik, Thomas, Reuben, Blotnick, Aaron M., Zhu, Yiwen, Sun, Xin, Pennacchio, Len A., Krogan, Nevan J., Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803373/
https://www.ncbi.nlm.nih.gov/pubmed/30814119
http://dx.doi.org/10.1242/dev.174086