Comprehensive Flux Modeling of Chlamydia trachomatis Proteome and qRT-PCR Data Indicate Biphasic Metabolic Differences Between Elementary Bodies and Reticulate Bodies During Infection

Metabolic adaptation to the host cell is important for obligate intracellular pathogens such as Chlamydia trachomatis (Ct). Here we infer the flux differences for Ct from proteome and qRT-PCR data by comprehensive pathway modeling. We compare the comparatively inert infectious elementary body (EB) a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Manli, Rajeeve, Karthika, Rudel, Thomas, Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803457/
https://www.ncbi.nlm.nih.gov/pubmed/31681215
http://dx.doi.org/10.3389/fmicb.2019.02350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803457/
https://www.ncbi.nlm.nih.gov/pubmed/31681215
http://dx.doi.org/10.3389/fmicb.2019.02350

Ejemplares similares