Elevations in Serum Dickkopf-1 and Disease Progression in Community-Dwelling Older Adults With Mild Cognitive Impairment and Mild-to-Moderate Alzheimer’s Disease

Background: Disruption of Wnt signaling has been implicated in dysfunctional synaptic plasticity, the degree of which correlates with Alzheimer’s disease severity. We sought to examine whether serum levels of Dickkopf-1 (Dkk-1), a Wnt antagonist, are associated with global disease progression in old...

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Detalles Bibliográficos
Autores principales: Tay, Laura, Leung, Bernard, Yeo, Audrey, Chan, Mark, Lim, Wee Shiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803458/
https://www.ncbi.nlm.nih.gov/pubmed/31680933
http://dx.doi.org/10.3389/fnagi.2019.00278

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