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Comparative Analysis of the CDR Loops of Antigen Receptors

The adaptive immune system uses two main types of antigen receptors: T-cell receptors (TCRs) and antibodies. While both proteins share a globally similar β-sandwich architecture, TCRs are specialized to recognize peptide antigens in the binding groove of the major histocompatibility complex, while a...

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Detalles Bibliográficos
Autores principales: Wong, Wing Ki, Leem, Jinwoo, Deane, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803477/
https://www.ncbi.nlm.nih.gov/pubmed/31681328
http://dx.doi.org/10.3389/fimmu.2019.02454