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The Controversial Role of PD-1 and Its Ligands in Gynecological Malignancies
The programmed death-1 (PD-1, CD279) receptor with its ligands, programmed death ligand 1 (PD-L1, CD274, B7-H1), and programmed death ligand 2 (PD-L2, CD273, B7-DC), are the key players of one of the immune checkpoint pathways inhibiting T-cell activation. PD-L1 and PD-L2 are expressed in different...
Autores principales: | Marinelli, Oliviero, Annibali, Daniela, Aguzzi, Cristina, Tuyaerts, Sandra, Amant, Frédéric, Morelli, Maria Beatrice, Santoni, Giorgio, Amantini, Consuelo, Maggi, Federica, Nabissi, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803534/ https://www.ncbi.nlm.nih.gov/pubmed/31681606 http://dx.doi.org/10.3389/fonc.2019.01073 |
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