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MiR-199a Inhibits Tumor Growth and Attenuates Chemoresistance by Targeting K-RAS via AKT and ERK Signalings
Glioma is the most malignant brain tumors in the world, the function and molecular mechanism of microRNA-199a (miR-199a) in glioma is not fully understood. Our research aims to investigate miR-199a/K-RAS axis in regulation of glioma tumor growth and chemoresistance. The function of miR-199a in gliom...
Autores principales: | Li, Wei, Wang, Lin, Ji, Xiang-Bo, Wang, Li-Hong, Ge, Xin, Liu, Wei-Tao, Chen, Ling, Zheng, Zhong, Shi, Zhu-Mei, Liu, Ling-Zhi, Lin, Marie C., Chen, Jie-Yu, Jiang, Bing-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803549/ https://www.ncbi.nlm.nih.gov/pubmed/31681604 http://dx.doi.org/10.3389/fonc.2019.01071 |
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