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MiR-199a Inhibits Tumor Growth and Attenuates Chemoresistance by Targeting K-RAS via AKT and ERK Signalings

Glioma is the most malignant brain tumors in the world, the function and molecular mechanism of microRNA-199a (miR-199a) in glioma is not fully understood. Our research aims to investigate miR-199a/K-RAS axis in regulation of glioma tumor growth and chemoresistance. The function of miR-199a in gliom...

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Detalles Bibliográficos
Autores principales: Li, Wei, Wang, Lin, Ji, Xiang-Bo, Wang, Li-Hong, Ge, Xin, Liu, Wei-Tao, Chen, Ling, Zheng, Zhong, Shi, Zhu-Mei, Liu, Ling-Zhi, Lin, Marie C., Chen, Jie-Yu, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803549/
https://www.ncbi.nlm.nih.gov/pubmed/31681604
http://dx.doi.org/10.3389/fonc.2019.01071

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