Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4

The recognition of PPxY viral Late domains by the third WW domain of the HECT-E3 ubiquitin ligase NEDD4 (hNEDD4-WW3) is essential for the completion of the budding process of numerous enveloped viruses, including Ebola, Marburg, HTLV1 or Rabies. hNEDD4-WW3 has been validated as a promising target fo...

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Detalles Bibliográficos
Autores principales: Iglesias-Bexiga, Manuel, Palencia, Andrés, Corbi-Verge, Carles, Martin-Malpartida, Pau, Blanco, Francisco J., Macias, Maria J., Cobos, Eva S., Luque, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803667/
https://www.ncbi.nlm.nih.gov/pubmed/31636332
http://dx.doi.org/10.1038/s41598-019-50701-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803667/
https://www.ncbi.nlm.nih.gov/pubmed/31636332
http://dx.doi.org/10.1038/s41598-019-50701-3

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