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Versatile format of minichaperone-based protein fusion system
Hydrophobic recombinant proteins often tend to aggregate upon expression into inclusion bodies and are difficult to refold. Producing them in soluble forms constitutes a common bottleneck problem. A fusion system for production of insoluble hydrophobic proteins in soluble stable forms with thermophi...
Autores principales: | Yurkova, Maria S., Sharapova, Olga A., Zenin, Vladimir A., Fedorov, Alexey N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803692/ https://www.ncbi.nlm.nih.gov/pubmed/31636289 http://dx.doi.org/10.1038/s41598-019-51015-0 |
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