Cargando…

Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity

Oligonucleotides with an antiproliferative activity for human cancer cells have attracted attention over the past decades; many of them have a G-quadruplex structure (GQ), and a cryptic target. In particular, DNA oligonucleotide HD1, a minimal GQ, could inhibit proliferation of some cancer cell line...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antipova, Olga, Samoylenkova, Nadezhda, Savchenko, Ekaterina, Zavyalova, Elena, Revishchin, Alexander, Pavlova, Galina, Kopylov, Alexey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803823/ https://www.ncbi.nlm.nih.gov/pubmed/31597343 http://dx.doi.org/10.3390/molecules24193625

Ejemplares similares

Covalent Bi-Modular Parallel and Antiparallel G-Quadruplex DNA Nanocostructs Reduce Viability of Patient Glioma Primary Cell Cultures
por: Legatova, Valeria, et al.
Publicado: (2021)

Evaluation of Antithrombotic Activity of Thrombin DNA Aptamers by a Murine Thrombosis Model
por: Zavyalova, Elena, et al.
Publicado: (2014)

A Combined Effect of G-Quadruplex and Neuro-Inducers as an Alternative Approach to Human Glioblastoma Therapy
por: Pavlova, Galina, et al.
Publicado: (2022)

The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36
por: Zavyalova, Elena, et al.
Publicado: (2017)

Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin
por: Zavyalova, Elena G., et al.
Publicado: (2019)

Improved in Vitro Efficacy of Gold Nanoconstructs by Increased Loading of G-quadruplex Aptamer
por: Dam, Duncan Hieu M., et al.
Publicado: (2014)

Antiparallel RNA G-quadruplex Formed by Human Telomere RNA Containing 8-Bromoguanosine
por: Xiao, Chao-Da, et al.
Publicado: (2017)

A Chimeric DNA/RNA Antiparallel Quadruplex with Improved Stability
por: Boyle, Elaina P., et al.
Publicado: (2022)

Enhancement of the Immunostimulatory Effect of Phosphodiester CpG Oligodeoxynucleotides by an Antiparallel Guanine-Quadruplex Structural Scaffold
por: Safitri, Fika Ayu, et al.
Publicado: (2021)

Neuroinductive properties of mGDNF depend on the producer, E. Coli or human cells
por: Shamadykova, Dzhirgala V., et al.
Publicado: (2021)

Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures
por: Mikek, Clinton G., et al.
Publicado: (2018)

The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA
por: Geng, Yanyan, et al.
Publicado: (2019)

Hybrid-type and two-tetrad antiparallel telomere DNA G-quadruplex structures in living human cells
por: Bao, Hong-Liang, et al.
Publicado: (2019)

Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases
por: Michalowski, Daniel, et al.
Publicado: (2008)

The Functional Role of Loops and Flanking Sequences of G-Quadruplex Aptamer to the Hemagglutinin of Influenza a Virus
por: Bizyaeva, Anastasia A., et al.
Publicado: (2021)

Structure of the human telomere in Na(+) solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity
por: Lim, Kah Wai, et al.
Publicado: (2013)

Formation and stabilization of the telomeric antiparallel G-quadruplex and inhibition of telomerase by novel benzothioxanthene derivatives with anti-tumor activity
por: Zhang, Wen, et al.
Publicado: (2015)

Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence
por: Zhou, Bo, et al.
Publicado: (2018)

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
por: Lago, Sara, et al.
Publicado: (2021)

Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core
por: Svetlova, Julia, et al.
Publicado: (2021)

Disordering of Human Telomeric G-Quadruplex with Novel Antiproliferative Anthrathiophenedione
por: Kaluzhny, Dmitry, et al.
Publicado: (2011)

Functional Analysis of Drosophila HSP70 Promoter with Different HSE Numbers in Human Cells
por: Kust, Nadezda, et al.
Publicado: (2014)

Transverse Impact on Rectangular Metal and Reinforced Concrete Beams Taking into Account Bimodularity of the Material
por: Beskopylny, Alexey, et al.
Publicado: (2020)

Structural and Functional Aspects of G-Quadruplex Aptamers Which Bind a Broad Range of Influenza A Viruses
por: Novoseltseva, Anastasia A., et al.
Publicado: (2020)

Classification of G-Quadruplex DNA on the Basis of the Quadruplex Twist Angle and Planarity of G-Quartets
por: Reshetnikov, R.V., et al.
Publicado: (2010)

Reversible induction of mitophagy by an optogenetic bimodular system
por: D’Acunzo, Pasquale, et al.
Publicado: (2019)

Exploring potential anticoagulant drug formulations using thrombin generation test
por: Zavyalova, Elena, et al.
Publicado: (2015)

Energy Transfer as A Driving Force in Nucleic Acid–Protein Interactions
por: Zavyalova, Elena, et al.
Publicado: (2019)

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
por: Ambrus, Attila, et al.
Publicado: (2006)

Phen‐DC(3) Induces Refolding of Human Telomeric DNA into a Chair‐Type Antiparallel G‐Quadruplex through Ligand Intercalation
por: Ghosh, Anirban, et al.
Publicado: (2022)

DNA G-Quadruplexes Contribute to CTCF Recruitment
por: Tikhonova, Polina, et al.
Publicado: (2021)

Reparative properties of human glioblastoma cells after single exposure to a wide range of X-ray doses
por: Pavlova, Galina, et al.
Publicado: (2022)

Thermoresponsive Magnetic Hydrogels as Theranostic Nanoconstructs
por: Jaiswal, Manish K., et al.
Publicado: (2014)

X-ray-Activatable Photodynamic Nanoconstructs
por: Overchuk, Marta, et al.
Publicado: (2020)

Bimodular high temperature planar oxygen gas sensor
por: Sun, Xiangcheng, et al.
Publicado: (2014)

Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties
por: Rocca, Roberta, et al.
Publicado: (2022)

G4 Matters—The Influence of G-Quadruplex Structural Elements on the Antiproliferative Properties of G-Rich Oligonucleotides
por: Roxo, Carolina, et al.
Publicado: (2021)

Semi-Infinite Structure Analysis with Bimodular Materials with Infinite Element
por: Huang, Wang, et al.
Publicado: (2022)

G-Quadruplexes in Nuclear Biomolecular Condensates
por: Pavlova, Iuliia, et al.
Publicado: (2023)

The antiparallel loops in gal DNA
por: Lia, Giuseppe, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_hji0tgvkuv0egd69o90jiqf1ku