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Atroxlysin-III, A Metalloproteinase from the Venom of the Peruvian Pit Viper Snake Bothrops atrox (Jergón) Induces Glycoprotein VI Shedding and Impairs Platelet Function
Atroxlysin-III (Atr-III) was purified from the venom of Bothrops atrox. This 56-kDa protein bears N-linked glycoconjugates and is a P-III hemorrhagic metalloproteinase. Its cDNA-deduced amino acid sequence reveals a multidomain structure including a proprotein, a metalloproteinase, a disintegrin-lik...
Autores principales: | Oliveira, Luciana S., Estevão-Costa, Maria Inácia, Alvarenga, Valéria G., Vivas-Ruiz, Dan E., Yarleque, Armando, Lima, Augusto Martins, Cavaco, Ana, Eble, Johannes A., Sanchez, Eladio F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803841/ https://www.ncbi.nlm.nih.gov/pubmed/31561469 http://dx.doi.org/10.3390/molecules24193489 |
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