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Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells

Our aim was to verify the potential ability of succinylacetone (SA) to inhibit mitochondrial function, thereby suppressing cancer cell proliferation. SA treatment caused apoptosis in HCT116 and HT29 cells, but not in SW480 cells, with mitochondria playing a key role. We checked for dysfunctional mit...

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Detalles Bibliográficos
Autores principales:	Lee, Phil Jun, Woo, Seung Je, Yoo, Hee Min, Cho, Namki, Kim, Hong Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803967/ https://www.ncbi.nlm.nih.gov/pubmed/31623369 http://dx.doi.org/10.3390/molecules24193575

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