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Co-Localization of DNA i-Motif-Forming Sequences and 5-Hydroxymethyl-cytosines in Human Embryonic Stem Cells

G-quadruplexes (G4s) and i-motifs (iMs) are tetraplex DNA structures. Sequences capable of forming G4/iMs are abundant near the transcription start sites (TSS) of several genes. G4/iMs affect gene expression in vitro. Depending on the gene, the presence of G4/iMs can enhance or suppress expression,...

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Detalles Bibliográficos
Autores principales:	Bhavsar-Jog, Yogini P., Van Dornshuld, Eric, Brooks, Tracy A., Tschumper, Gregory S., Wadkins, Randy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804057/ https://www.ncbi.nlm.nih.gov/pubmed/31597270 http://dx.doi.org/10.3390/molecules24193619

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