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Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum
Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U–Z (1–8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by (1)H...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804164/ https://www.ncbi.nlm.nih.gov/pubmed/31561557 http://dx.doi.org/10.3390/molecules24193498 |
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| author | Westphal, Klaus Ringsborg Werner, Manuela Ilse Helga Nielsen, Katrine Amalie Hamborg Sørensen, Jens Laurids Andrushchenko, Valery Winde, Jacob Hertz, Morten Jensen, Mikkel Astrup Mortensen, Mathilde Lauge Bouř, Petr Sondergaard, Teis Esben Wimmer, Reinhard |
| author_facet | Westphal, Klaus Ringsborg Werner, Manuela Ilse Helga Nielsen, Katrine Amalie Hamborg Sørensen, Jens Laurids Andrushchenko, Valery Winde, Jacob Hertz, Morten Jensen, Mikkel Astrup Mortensen, Mathilde Lauge Bouř, Petr Sondergaard, Teis Esben Wimmer, Reinhard |
| author_sort | Westphal, Klaus Ringsborg |
| collection | PubMed |
| description | Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U–Z (1–8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by (1)H coupling and NOESY/ROESY experiments. Absolute stereochemistry established for 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum. |
| format | Online Article Text |
| id | pubmed-6804164 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-68041642019-11-18 Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum Westphal, Klaus Ringsborg Werner, Manuela Ilse Helga Nielsen, Katrine Amalie Hamborg Sørensen, Jens Laurids Andrushchenko, Valery Winde, Jacob Hertz, Morten Jensen, Mikkel Astrup Mortensen, Mathilde Lauge Bouř, Petr Sondergaard, Teis Esben Wimmer, Reinhard Molecules Article Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U–Z (1–8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by (1)H coupling and NOESY/ROESY experiments. Absolute stereochemistry established for 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum. MDPI 2019-09-26 /pmc/articles/PMC6804164/ /pubmed/31561557 http://dx.doi.org/10.3390/molecules24193498 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Westphal, Klaus Ringsborg Werner, Manuela Ilse Helga Nielsen, Katrine Amalie Hamborg Sørensen, Jens Laurids Andrushchenko, Valery Winde, Jacob Hertz, Morten Jensen, Mikkel Astrup Mortensen, Mathilde Lauge Bouř, Petr Sondergaard, Teis Esben Wimmer, Reinhard Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title | Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title_full | Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title_fullStr | Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title_full_unstemmed | Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title_short | Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum |
| title_sort | characterization of eight novel spiroleptosphols from fusarium avenaceum |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804164/ https://www.ncbi.nlm.nih.gov/pubmed/31561557 http://dx.doi.org/10.3390/molecules24193498 |
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