Cargando…

Spray Congealing: An Emerging Technology to Prepare Solid Dispersions with Enhanced Oral Bioavailability of Poorly Water Soluble Drugs

The low and variable oral bioavailability of poorly water soluble drugs remains a major concern for the pharmaceutical industry. Spray congealing is an emerging technology for the production of solid dispersion to enhance the bioavailability of poorly soluble drugs by using low-melting hydrophilic e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertoni, Serena, Albertini, Beatrice, Passerini, Nadia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804277/ https://www.ncbi.nlm.nih.gov/pubmed/31557815 http://dx.doi.org/10.3390/molecules24193471

Ejemplares similares

Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances
por: Bertoni, Serena, et al.
Publicado: (2020)

Combining Mechanochemistry and Spray Congealing for New Praziquantel Pediatric Formulations in Schistosomiasis Treatment
por: Albertini, Beatrice, et al.
Publicado: (2019)

Solid Lipid Microparticles by Spray Congealing of Water/Oil Emulsion: An Effective/Versatile Loading Strategy for a Highly Soluble Drug
por: Candiani, Alessandro, et al.
Publicado: (2022)

Liquid Lipids Act as Polymorphic Modifiers of Tristearin-Based Formulations Produced by Melting Technologies
por: Bertoni, Serena, et al.
Publicado: (2021)

Insoluble Polymers in Solid Dispersions for Improving Bioavailability of Poorly Water-Soluble Drugs
por: Tran, Thao T.D., et al.
Publicado: (2020)

Glutathione-Loaded Solid Lipid Microparticles as Innovative Delivery System for Oral Antioxidant Therapy
por: Bertoni, Serena, et al.
Publicado: (2019)

Highly Water-Soluble Solid Dispersions of Honokiol: Preparation, Solubility, and Bioavailability Studies and Anti-Tumor Activity Evaluation
por: Wang, Li, et al.
Publicado: (2019)

Solid Lipid Microparticles for Oral Delivery of Catalase: Focus on the Protein Structural Integrity and Gastric Protection
por: Bertoni, Serena, et al.
Publicado: (2020)

Enhanced Solubility and Bioavailability of Apigenin via Preparation of Solid Dispersions of Mesoporous Silica Nanoparticles
por: Huang, Yannian, et al.
Publicado: (2019)

Improvement in solubility of poor water-soluble drugs by solid dispersion
por: Sareen, Swati, et al.
Publicado: (2012)

Fundamental aspects of solid dispersion technology for poorly soluble drugs
por: Huang, Yanbin, et al.
Publicado: (2014)

Revealing facts behind spray dried solid dispersion technology used for solubility enhancement
por: Patel, Bhavesh B., et al.
Publicado: (2015)

Enhanced Oral Bioavailability of Resveratrol by Using Neutralized Eudragit E Solid Dispersion Prepared via Spray Drying
por: Ha, Eun-Sol, et al.
Publicado: (2021)

Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs
por: Zhang, Xingwang, et al.
Publicado: (2018)

Formulation of Lipid-Based Tableted Spray-Congealed Microparticles for Sustained Release of Vildagliptin: In Vitro and In Vivo Studies
por: Al Zahabi, Khaled H., et al.
Publicado: (2021)

Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion
por: Altamimi, Mohammad A., et al.
Publicado: (2019)

Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability
por: Han, Fei, et al.
Publicado: (2019)

Mechanochemical preparation of chrysomycin A self-micelle solid dispersion with improved solubility and enhanced oral bioavailability
por: Xu, Zhuomin, et al.
Publicado: (2021)

Preparation of a camptothecin analog FLQY2 self-micelle solid dispersion with improved solubility and bioavailability
por: Wang, Yi, et al.
Publicado: (2022)

Spray-Dried Amorphous Solid Dispersions of Atorvastatin Calcium for Improved Supersaturation and Oral Bioavailability
por: Kwon, Jaewook, et al.
Publicado: (2019)

Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer formulation techniques, current marketed scenario and patents
por: Alshehri, Sultan, et al.
Publicado: (2020)

Molecular Interactions in Solid Dispersions of Poorly Water-Soluble Drugs
por: Tran, Thao T. D., et al.
Publicado: (2020)

Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs
por: Tran, Phuong, et al.
Publicado: (2019)

Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator
por: Tanaka, Ryoma, et al.
Publicado: (2019)

Solvent-Free Fabrication of Biphasic Lipid-Based Microparticles with Tunable Structure
por: Bertoni, Serena, et al.
Publicado: (2021)

Nanocrystalization: An Emerging Technology to Enhance the  Bioavailability of Poorly Soluble Drugs
por: Joshi, Kavita, et al.
Publicado: (2019)

Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance
por: Pinto, Joana T., et al.
Publicado: (2021)

Improved Bioavailability and High Photostability of Methotrexate by Spray-Dried Surface-Attached Solid Dispersion with an Aqueous Medium
por: Giri, Bhupendra Raj, et al.
Publicado: (2021)

Cefdinir Solid Dispersion Composed of Hydrophilic Polymers with Enhanced Solubility, Dissolution, and Bioavailability in Rats
por: Cho, Hyun-Jong, et al.
Publicado: (2017)

Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan
por: Giri, Bhupendra Raj, et al.
Publicado: (2021)

Exploring the Solubility and Bioavailability of Sodium Salt and Its Free Acid Solid Dispersions of Dolutegravir
por: Yarlagadda, Dani Lakshman, et al.
Publicado: (2023)

Atorvastatin solid dispersion for bioavailability enhancement
por: Shamsuddin,, et al.
Publicado: (2016)

Solubility Enhancement of a Poorly Water Soluble Drug by Forming Solid Dispersions using Mechanochemical Activation
por: Rojas-Oviedo, I., et al.
Publicado: (2012)

A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs
por: Tekade, Avinash Ramrao, et al.
Publicado: (2020)

Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion
por: Ding, Shu-min, et al.
Publicado: (2014)

Manufacturing Different Types of Solid Dispersions of BCS Class IV Polyphenol (Daidzein) by Spray Drying: Formulation and Bioavailability
por: Panizzon, Gean Pier, et al.
Publicado: (2019)

Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
por: Rashid, Rehmana, et al.
Publicado: (2015)

Starches of two water yam (Dioscorea alata) varieties used as congeals in yogurt production
por: Tortoe, Charles, et al.
Publicado: (2019)

Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods
por: Školáková, Tereza, et al.
Publicado: (2019)

Preparation of Apixaban Solid Dispersion for the Enhancement of Apixaban Solubility and Permeability
por: Lee, Juseung, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_67fiet0cfcbiontb7ol8flckj5