Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis

OBJECTIVES: To gain insight into the propagation of miltefosine (MIL) resistance in visceral leishmaniasis, this laboratory study explored development of resistant parasites with a defective miltefosine transporter (MT) in sand flies. METHODS: Infectivity, colonization of stomodeal valve and metacyc...

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Detalles Bibliográficos
Autores principales: Van Bockstal, Lieselotte, Sádlová, Jovana, Suau, Hamide Aslan, Hendrickx, Sarah, Meneses, Claudio, Kamhawi, Shaden, Volf, Petr, Maes, Louis, Caljon, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804374/
https://www.ncbi.nlm.nih.gov/pubmed/31525614
http://dx.doi.org/10.1016/j.ijpddr.2019.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804374/
https://www.ncbi.nlm.nih.gov/pubmed/31525614
http://dx.doi.org/10.1016/j.ijpddr.2019.09.003

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