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Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia

BACKGROUND: Treatment of Congenital Psuedarthrosis of Tibia (CPT) often poses significant challenges due to difficulty in achieving union and subsequent complications like refractures, implant failures, etc. Our new comprehensive protocol is aimed at achieving crossunion between the tibia and fibula...

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Autores principales: Vaidya, Sandeep Vijaykumar, Aroojis, Alaric, Mehta, Rujuta, Agashe, Mandar Vikas, Dhawale, Arjun, Bansal, Ankita Vijay, Sarathy, Kailash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804390/
https://www.ncbi.nlm.nih.gov/pubmed/31673175
http://dx.doi.org/10.4103/ortho.IJOrtho_155_19
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author Vaidya, Sandeep Vijaykumar
Aroojis, Alaric
Mehta, Rujuta
Agashe, Mandar Vikas
Dhawale, Arjun
Bansal, Ankita Vijay
Sarathy, Kailash
author_facet Vaidya, Sandeep Vijaykumar
Aroojis, Alaric
Mehta, Rujuta
Agashe, Mandar Vikas
Dhawale, Arjun
Bansal, Ankita Vijay
Sarathy, Kailash
author_sort Vaidya, Sandeep Vijaykumar
collection PubMed
description BACKGROUND: Treatment of Congenital Psuedarthrosis of Tibia (CPT) often poses significant challenges due to difficulty in achieving union and subsequent complications like refractures, implant failures, etc. Our new comprehensive protocol is aimed at achieving crossunion between the tibia and fibula. AIMS AND OBJECTIVES: The aim of the present study is to evaluate the short-term results of our new protocol and to compare the results with our previously used techniques. MATERIALS AND METHODS: 10 patients with mean age 2.35 years (1 to 6.5 years) who were treated by our new comprehensive protocol were included in Group A, and 11 patients with mean age 2 years (1 to 5.5 years) who primarily underwent intramedullary rodding with bone graft were included in Group B. The new comprehensive protocol consisted of pre-operative Zolendronate infusion, surgery consisting of intramedullary fixation of tibia supplemented with Ilizarov ring fixator and bone grafting aimed at achieving tibia-fibula cross-union. Retrospective evaluation of serial radiographs was performed and outcomes with respect to union and subsequent complications were analysed. RESULTS: 10/10 (100%) patients in Group A united, whereas union was achieved in only 8/11 (72%) patients in Group B. The index surgery was successful in achieving union in all 10 patients in Group A, whereas in Group B 2.25 (1 to 4) surgeries were needed to achieve union. The time to union was significantly shorter in Group A (4.68 months) as compared to Group B (30.88 months). The cross sectional area of union was significantly greater in Group A (3.82 cm2) as compared to Group B (1.18 cm2). One patient in Group A needed a subsequent corrective osteotomy for tibial valgus, and one patient underwent tibia lengthening; whereas in Group B, two patients needed corrective osteotomes for residual malaligments. CONCLUSION: Our study demonstrates that the new comprehensive protocol is extremely effective for achieving sound union in Congenital Pseudarthrosis of Tibia.
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spelling pubmed-68043902019-11-01 Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia Vaidya, Sandeep Vijaykumar Aroojis, Alaric Mehta, Rujuta Agashe, Mandar Vikas Dhawale, Arjun Bansal, Ankita Vijay Sarathy, Kailash Indian J Orthop Original Article BACKGROUND: Treatment of Congenital Psuedarthrosis of Tibia (CPT) often poses significant challenges due to difficulty in achieving union and subsequent complications like refractures, implant failures, etc. Our new comprehensive protocol is aimed at achieving crossunion between the tibia and fibula. AIMS AND OBJECTIVES: The aim of the present study is to evaluate the short-term results of our new protocol and to compare the results with our previously used techniques. MATERIALS AND METHODS: 10 patients with mean age 2.35 years (1 to 6.5 years) who were treated by our new comprehensive protocol were included in Group A, and 11 patients with mean age 2 years (1 to 5.5 years) who primarily underwent intramedullary rodding with bone graft were included in Group B. The new comprehensive protocol consisted of pre-operative Zolendronate infusion, surgery consisting of intramedullary fixation of tibia supplemented with Ilizarov ring fixator and bone grafting aimed at achieving tibia-fibula cross-union. Retrospective evaluation of serial radiographs was performed and outcomes with respect to union and subsequent complications were analysed. RESULTS: 10/10 (100%) patients in Group A united, whereas union was achieved in only 8/11 (72%) patients in Group B. The index surgery was successful in achieving union in all 10 patients in Group A, whereas in Group B 2.25 (1 to 4) surgeries were needed to achieve union. The time to union was significantly shorter in Group A (4.68 months) as compared to Group B (30.88 months). The cross sectional area of union was significantly greater in Group A (3.82 cm2) as compared to Group B (1.18 cm2). One patient in Group A needed a subsequent corrective osteotomy for tibial valgus, and one patient underwent tibia lengthening; whereas in Group B, two patients needed corrective osteotomes for residual malaligments. CONCLUSION: Our study demonstrates that the new comprehensive protocol is extremely effective for achieving sound union in Congenital Pseudarthrosis of Tibia. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6804390/ /pubmed/31673175 http://dx.doi.org/10.4103/ortho.IJOrtho_155_19 Text en Copyright: © 2019 Indian Journal of Orthopaedics http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Vaidya, Sandeep Vijaykumar
Aroojis, Alaric
Mehta, Rujuta
Agashe, Mandar Vikas
Dhawale, Arjun
Bansal, Ankita Vijay
Sarathy, Kailash
Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title_full Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title_fullStr Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title_full_unstemmed Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title_short Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia
title_sort short term results of a new comprehensive protocol for the management of congenital pseudarthrosis of the tibia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804390/
https://www.ncbi.nlm.nih.gov/pubmed/31673175
http://dx.doi.org/10.4103/ortho.IJOrtho_155_19
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