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Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven pro-tumorigenic senescent secretion

It is critical to regulate the senescence-associated secretory phenotype (SASP) due to its effect on promoting malignant phenotypes and limiting the efficiency of cancer therapy. In this study, we demonstrated that marchantin M (Mar-M, a naturally occurring bisbibenzyl) suppressed pro-inflammatory S...

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Detalles Bibliográficos
Autores principales:	Niu, Huanmin, Qian, Lilin, Sun, Bin, Liu, Wenjian, Wang, Fang, Wang, Qian, Ji, Xiaotian, Luo, Yanhai, Nesa, Effat Un, Lou, Hongxiang, Yuan, Huiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804491/ https://www.ncbi.nlm.nih.gov/pubmed/31649843 http://dx.doi.org/10.1016/j.apsb.2019.08.007

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