Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient

PURPOSE: To report a case of an immunocompetent 64-year-old man who developed cytomegalovirus (CMV) retinitis after using topical difluprednate. OBSERVATIONS: A 64-year-old man with type 2 diabetes developed hemorrhagic retinitis while using topical difluprednate after penetrating keratoplasty. Poly...

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Detalles Bibliográficos
Autores principales: Kaplan, Richard I., Do, Brian K., Gentile, Ronald C., Kedhar, Sanjay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804500/
https://www.ncbi.nlm.nih.gov/pubmed/31650081
http://dx.doi.org/10.1016/j.ajoc.2019.100552
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author Kaplan, Richard I.
Do, Brian K.
Gentile, Ronald C.
Kedhar, Sanjay R.
author_facet Kaplan, Richard I.
Do, Brian K.
Gentile, Ronald C.
Kedhar, Sanjay R.
author_sort Kaplan, Richard I.
collection PubMed
description PURPOSE: To report a case of an immunocompetent 64-year-old man who developed cytomegalovirus (CMV) retinitis after using topical difluprednate. OBSERVATIONS: A 64-year-old man with type 2 diabetes developed hemorrhagic retinitis while using topical difluprednate after penetrating keratoplasty. Polymerase chain reaction of the vitreous was positive for CMV DNA. Complete blood count was within normal limits and 4th generation human immunodeficiency virus assay was negative. The retinitis resolved with oral valgancyclovir and intravitreal foscarnet injections. CONCLUSION AND IMPORTANCE: CMV retinitis may occur after topical difluprednate in an immunocompetent patient.
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spelling pubmed-68045002019-10-24 Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient Kaplan, Richard I. Do, Brian K. Gentile, Ronald C. Kedhar, Sanjay R. Am J Ophthalmol Case Rep Case Report PURPOSE: To report a case of an immunocompetent 64-year-old man who developed cytomegalovirus (CMV) retinitis after using topical difluprednate. OBSERVATIONS: A 64-year-old man with type 2 diabetes developed hemorrhagic retinitis while using topical difluprednate after penetrating keratoplasty. Polymerase chain reaction of the vitreous was positive for CMV DNA. Complete blood count was within normal limits and 4th generation human immunodeficiency virus assay was negative. The retinitis resolved with oral valgancyclovir and intravitreal foscarnet injections. CONCLUSION AND IMPORTANCE: CMV retinitis may occur after topical difluprednate in an immunocompetent patient. Elsevier 2019-09-10 /pmc/articles/PMC6804500/ /pubmed/31650081 http://dx.doi.org/10.1016/j.ajoc.2019.100552 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kaplan, Richard I.
Do, Brian K.
Gentile, Ronald C.
Kedhar, Sanjay R.
Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title_full Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title_fullStr Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title_full_unstemmed Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title_short Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
title_sort cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804500/
https://www.ncbi.nlm.nih.gov/pubmed/31650081
http://dx.doi.org/10.1016/j.ajoc.2019.100552
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