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Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory

OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV posit...

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Autores principales: Lorenzi, Adriana Tarlá, Fregnani, José Humberto, Villa, Luisa Lina, Sichero, Laura, Nunes, Emily Montosa, Longatto-Filho, Adhemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804508/
https://www.ncbi.nlm.nih.gov/pubmed/31539646
http://dx.doi.org/10.1016/j.pvr.2019.100186
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author Lorenzi, Adriana Tarlá
Fregnani, José Humberto
Villa, Luisa Lina
Sichero, Laura
Nunes, Emily Montosa
Longatto-Filho, Adhemar
author_facet Lorenzi, Adriana Tarlá
Fregnani, José Humberto
Villa, Luisa Lina
Sichero, Laura
Nunes, Emily Montosa
Longatto-Filho, Adhemar
author_sort Lorenzi, Adriana Tarlá
collection PubMed
description OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. RESULTS: Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (<3%) were: HPV-70, HPV-11 and HPV-26. CONCLUSIONS: The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates.
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spelling pubmed-68045082019-10-24 Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory Lorenzi, Adriana Tarlá Fregnani, José Humberto Villa, Luisa Lina Sichero, Laura Nunes, Emily Montosa Longatto-Filho, Adhemar Papillomavirus Res Article OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. RESULTS: Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (<3%) were: HPV-70, HPV-11 and HPV-26. CONCLUSIONS: The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates. Elsevier 2019-09-17 /pmc/articles/PMC6804508/ /pubmed/31539646 http://dx.doi.org/10.1016/j.pvr.2019.100186 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lorenzi, Adriana Tarlá
Fregnani, José Humberto
Villa, Luisa Lina
Sichero, Laura
Nunes, Emily Montosa
Longatto-Filho, Adhemar
Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title_full Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title_fullStr Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title_full_unstemmed Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title_short Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
title_sort diversity of human papillomavirus typing among women population living in rural and remote areas of brazilian territory
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804508/
https://www.ncbi.nlm.nih.gov/pubmed/31539646
http://dx.doi.org/10.1016/j.pvr.2019.100186
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