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Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory
OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV posit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804508/ https://www.ncbi.nlm.nih.gov/pubmed/31539646 http://dx.doi.org/10.1016/j.pvr.2019.100186 |
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author | Lorenzi, Adriana Tarlá Fregnani, José Humberto Villa, Luisa Lina Sichero, Laura Nunes, Emily Montosa Longatto-Filho, Adhemar |
author_facet | Lorenzi, Adriana Tarlá Fregnani, José Humberto Villa, Luisa Lina Sichero, Laura Nunes, Emily Montosa Longatto-Filho, Adhemar |
author_sort | Lorenzi, Adriana Tarlá |
collection | PubMed |
description | OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. RESULTS: Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (<3%) were: HPV-70, HPV-11 and HPV-26. CONCLUSIONS: The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates. |
format | Online Article Text |
id | pubmed-6804508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-68045082019-10-24 Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory Lorenzi, Adriana Tarlá Fregnani, José Humberto Villa, Luisa Lina Sichero, Laura Nunes, Emily Montosa Longatto-Filho, Adhemar Papillomavirus Res Article OBJECTIVES: Genotyping HPV from samples tested positive to careHPV™ assay in rural and remote areas of Brazilian territory. METHODS: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV™ hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. RESULTS: Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (<3%) were: HPV-70, HPV-11 and HPV-26. CONCLUSIONS: The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates. Elsevier 2019-09-17 /pmc/articles/PMC6804508/ /pubmed/31539646 http://dx.doi.org/10.1016/j.pvr.2019.100186 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lorenzi, Adriana Tarlá Fregnani, José Humberto Villa, Luisa Lina Sichero, Laura Nunes, Emily Montosa Longatto-Filho, Adhemar Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title | Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title_full | Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title_fullStr | Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title_full_unstemmed | Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title_short | Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory |
title_sort | diversity of human papillomavirus typing among women population living in rural and remote areas of brazilian territory |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804508/ https://www.ncbi.nlm.nih.gov/pubmed/31539646 http://dx.doi.org/10.1016/j.pvr.2019.100186 |
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