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A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy

INTRODUCTION: Neuroinflammation, which contributes to neurodegeneration, is a consistent hallmark of dementia. Emerging evidence suggests that systemic inflammation also contributes to disease progression. METHODS: The ability of systemically administered lipopolysaccharide (LPS - 500 μg/kg) to effe...

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Detalles Bibliográficos
Autores principales:	Torvell, Megan, Hampton, David W., Connick, Peter, MacLullich, Alasdair M.J., Cunningham, Colm, Chandran, Siddharthan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804509/ https://www.ncbi.nlm.nih.gov/pubmed/31650014 http://dx.doi.org/10.1016/j.trci.2019.09.001

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