Cargando…
Immunotherapeutic Challenges for Pediatric Cancers
Solid tumors contain a mixture of malignant cells and non-malignant infiltrating cells that often create a chronic inflammatory and immunosuppressive microenvironment that restricts immunotherapeutic approaches. Although childhood and adult cancers share some similarities related to microenvironment...
Autores principales: | Hutzen, Brian, Ghonime, Mohammed, Lee, Joel, Mardis, Elaine R., Wang, Ruoning, Lee, Dean A., Cairo, Mitchell S., Roberts, Ryan D., Cripe, Timothy P., Cassady, Kevin A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804520/ https://www.ncbi.nlm.nih.gov/pubmed/31650024 http://dx.doi.org/10.1016/j.omto.2019.08.005 |
Ejemplares similares
-
Pediatric versus adult high grade glioma: Immunotherapeutic and genomic considerations
por: Aggarwal, Payal, et al.
Publicado: (2022) -
The Antiviral Apparatus: STING and Oncolytic Virus Restriction
por: Lee, Joel, et al.
Publicado: (2019) -
Immunotherapies for pediatric cancer: current landscape and future perspectives
por: Hutzen, Brian, et al.
Publicado: (2019) -
Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma
por: Wedekind, Mary Frances, et al.
Publicado: (2021) -
STING Restricts oHSV Replication and Spread in Resistant MPNSTs but Is Dispensable for Basal IFN-Stimulated Gene Upregulation
por: Lee, Joel M., et al.
Publicado: (2019)