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2519: A quantitative disintegration method to evaluate polymeric films

OBJECTIVES/SPECIFIC AIMS: To establish an in vitro quantitative method for the evaluation of polymeric film disintegration that can be applied to predict in vivo behavior. METHODS/STUDY POPULATION: Two clinically advanced vaginal microbicide film products containing tenofovir and dapivirine were use...

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Detalles Bibliográficos
Autores principales: Grab, Sheila, Cosgrove Sweeney, Yvonne, Patton, Dorothy L., Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804541/
http://dx.doi.org/10.1017/cts.2017.238