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Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis
Transient receptor potential vanilloid 4 (TRPV4) has been implicated in many disease conditions also in the lung. Its activation leads to an increase endothelial permeability in an intracellular calcium-influx dependent manner. We investigated its function in vitro on primary human endothelial cells...
Autores principales: | Pairet, N., Mang, S., Kiechle, T., Laufhäger, N., Dietl, P., Lamb, D.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804647/ https://www.ncbi.nlm.nih.gov/pubmed/31650038 http://dx.doi.org/10.1016/j.bbrep.2019.100672 |
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