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Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians
INTRODUCTION: We assessed the sensitivity and specificity of the Modified Mini–Mental State Examination (3MS) in predicting dementia and cognitive impairment in Māori (indigenous people of New Zealand) and non-Māori octogenarians. METHODS: A subsample of participants from Life and Living in Advanced...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804777/ https://www.ncbi.nlm.nih.gov/pubmed/31650011 http://dx.doi.org/10.1016/j.trci.2019.08.006 |
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author | Zawaly, Kristina Moyes, Simon A. Wood, Phil C. Cheung, Gary Rolleston, Anna Buetow, Stephen Tippett, Lynette Kerse, Ngaire |
author_facet | Zawaly, Kristina Moyes, Simon A. Wood, Phil C. Cheung, Gary Rolleston, Anna Buetow, Stephen Tippett, Lynette Kerse, Ngaire |
author_sort | Zawaly, Kristina |
collection | PubMed |
description | INTRODUCTION: We assessed the sensitivity and specificity of the Modified Mini–Mental State Examination (3MS) in predicting dementia and cognitive impairment in Māori (indigenous people of New Zealand) and non-Māori octogenarians. METHODS: A subsample of participants from Life and Living in Advanced Age: a Cohort Study in New Zealand were recruited to determine the 3MS diagnostic accuracy compared with the reference standard. RESULTS: Seventy-three participants (44% Māori) completed the 3MS and reference standard assessments. The 3MS demonstrated strong diagnostic accuracy to detect dementia with areas under the curve of 0.87 for Māori and 0.9 for non-Māori. Our cutoffs displayed ethnic variability and are approximately 5 points greater than those commonly applied. Cognitive impairment yielded low accuracy, and discriminatory power was not established. DISCUSSION: Cutoffs that are not age or ethnically appropriate may compromise the accuracy of cognitive screens. Consequently, older age and indigeneity increase the risk of mislabeled cognitive status. |
format | Online Article Text |
id | pubmed-6804777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-68047772019-10-24 Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians Zawaly, Kristina Moyes, Simon A. Wood, Phil C. Cheung, Gary Rolleston, Anna Buetow, Stephen Tippett, Lynette Kerse, Ngaire Alzheimers Dement (N Y) Featured Article INTRODUCTION: We assessed the sensitivity and specificity of the Modified Mini–Mental State Examination (3MS) in predicting dementia and cognitive impairment in Māori (indigenous people of New Zealand) and non-Māori octogenarians. METHODS: A subsample of participants from Life and Living in Advanced Age: a Cohort Study in New Zealand were recruited to determine the 3MS diagnostic accuracy compared with the reference standard. RESULTS: Seventy-three participants (44% Māori) completed the 3MS and reference standard assessments. The 3MS demonstrated strong diagnostic accuracy to detect dementia with areas under the curve of 0.87 for Māori and 0.9 for non-Māori. Our cutoffs displayed ethnic variability and are approximately 5 points greater than those commonly applied. Cognitive impairment yielded low accuracy, and discriminatory power was not established. DISCUSSION: Cutoffs that are not age or ethnically appropriate may compromise the accuracy of cognitive screens. Consequently, older age and indigeneity increase the risk of mislabeled cognitive status. Elsevier 2019-10-07 /pmc/articles/PMC6804777/ /pubmed/31650011 http://dx.doi.org/10.1016/j.trci.2019.08.006 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Featured Article Zawaly, Kristina Moyes, Simon A. Wood, Phil C. Cheung, Gary Rolleston, Anna Buetow, Stephen Tippett, Lynette Kerse, Ngaire Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title | Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title_full | Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title_fullStr | Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title_full_unstemmed | Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title_short | Diagnostic accuracy of a global cognitive screen for Māori and non-Māori octogenarians |
title_sort | diagnostic accuracy of a global cognitive screen for māori and non-māori octogenarians |
topic | Featured Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804777/ https://www.ncbi.nlm.nih.gov/pubmed/31650011 http://dx.doi.org/10.1016/j.trci.2019.08.006 |
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