Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

Quiescence is essential for the long-term maintenance of adult stem cells but how stem cells maintain quiescence is poorly understood. Here, we show that neural stem cells (NSCs) in the adult mouse hippocampus actively transcribe the pro-activation factor Ascl1 regardless of their activated or quies...

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Detalles Bibliográficos
Autores principales: Blomfield, Isabelle Maria, Rocamonde, Brenda, Masdeu, Maria del Mar, Mulugeta, Eskeatnaf, Vaga, Stefania, van den Berg, Debbie LC, Huillard, Emmanuelle, Guillemot, François, Urbán, Noelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805120/
https://www.ncbi.nlm.nih.gov/pubmed/31552825
http://dx.doi.org/10.7554/eLife.48561

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