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Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis

Background and study aims  This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions. Patients and methods  This study included 132 consecutive lesions sampled by endo...

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Autores principales: Fujita, Akashi, Ryozawa, Shomei, Mizuide, Masafumi, Araki, Ryuichiro, Nagata, Koji, Tanisaka, Yuki, Harada, Maiko, Ogawa, Tomoya, Tashima, Tomoaki, Nonaka, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805192/
https://www.ncbi.nlm.nih.gov/pubmed/31673602
http://dx.doi.org/10.1055/a-0957-3005
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author Fujita, Akashi
Ryozawa, Shomei
Mizuide, Masafumi
Araki, Ryuichiro
Nagata, Koji
Tanisaka, Yuki
Harada, Maiko
Ogawa, Tomoya
Tashima, Tomoaki
Nonaka, Kouichi
author_facet Fujita, Akashi
Ryozawa, Shomei
Mizuide, Masafumi
Araki, Ryuichiro
Nagata, Koji
Tanisaka, Yuki
Harada, Maiko
Ogawa, Tomoya
Tashima, Tomoaki
Nonaka, Kouichi
author_sort Fujita, Akashi
collection PubMed
description Background and study aims  This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions. Patients and methods  This study included 132 consecutive lesions sampled by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) using a 22-G conventional needle and 95 consecutive lesions evaluated by EUS-FNB using a 22-G Franseen needle to evaluate solid pancreatic lesions at our medical center between July 2013 and November 2018. We used propensity-matched analysis with adjustment for confounders. Patient data were analyzed retrospectively. Results  Diagnostic accuracy was higher in the Franseen needle group (Group F; 91.6 %, 87 /95) than in the conventional needle group (Group C; 86.3 %, 82 /95), showing no significant difference ( P  = 0.36). In Group F, diagnostic accuracies for pancreatic head lesions and lesions sampled by transduodenal puncture were 98.0 % (48/49) and 97.9 % (46/47), respectively. These values were significantly higher than values in Group C ( P  = 0.013, 0.01). Group F displayed a significantly lower number of punctures. In terms of differentiating benign from malignant lesions, Group C showed 85.1 % sensitivity (74/87), 100 % specificity (8/8), 100 % positive predictive value (74/74), and 38.1 % negative predictive value (8/21), compared to values of 90.1 % (73/81), 100 % (14/14), 100 % (73/73), and 63.6 % (14/22), respectively, in Group F. Sensitivity and negative predictive value were better in Group F. Conclusions  Franseen needles for EUS-FNB of solid pancreatic lesions offer similar puncture performance at different lesion sites while requiring fewer punctures than conventional needles.
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spelling pubmed-68051922019-11-01 Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis Fujita, Akashi Ryozawa, Shomei Mizuide, Masafumi Araki, Ryuichiro Nagata, Koji Tanisaka, Yuki Harada, Maiko Ogawa, Tomoya Tashima, Tomoaki Nonaka, Kouichi Endosc Int Open Background and study aims  This study aimed to investigate the diagnostic accuracy and utility of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) performed using a Franseen needle on solid pancreatic lesions. Patients and methods  This study included 132 consecutive lesions sampled by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) using a 22-G conventional needle and 95 consecutive lesions evaluated by EUS-FNB using a 22-G Franseen needle to evaluate solid pancreatic lesions at our medical center between July 2013 and November 2018. We used propensity-matched analysis with adjustment for confounders. Patient data were analyzed retrospectively. Results  Diagnostic accuracy was higher in the Franseen needle group (Group F; 91.6 %, 87 /95) than in the conventional needle group (Group C; 86.3 %, 82 /95), showing no significant difference ( P  = 0.36). In Group F, diagnostic accuracies for pancreatic head lesions and lesions sampled by transduodenal puncture were 98.0 % (48/49) and 97.9 % (46/47), respectively. These values were significantly higher than values in Group C ( P  = 0.013, 0.01). Group F displayed a significantly lower number of punctures. In terms of differentiating benign from malignant lesions, Group C showed 85.1 % sensitivity (74/87), 100 % specificity (8/8), 100 % positive predictive value (74/74), and 38.1 % negative predictive value (8/21), compared to values of 90.1 % (73/81), 100 % (14/14), 100 % (73/73), and 63.6 % (14/22), respectively, in Group F. Sensitivity and negative predictive value were better in Group F. Conclusions  Franseen needles for EUS-FNB of solid pancreatic lesions offer similar puncture performance at different lesion sites while requiring fewer punctures than conventional needles. © Georg Thieme Verlag KG 2019-11 2019-10-22 /pmc/articles/PMC6805192/ /pubmed/31673602 http://dx.doi.org/10.1055/a-0957-3005 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Fujita, Akashi
Ryozawa, Shomei
Mizuide, Masafumi
Araki, Ryuichiro
Nagata, Koji
Tanisaka, Yuki
Harada, Maiko
Ogawa, Tomoya
Tashima, Tomoaki
Nonaka, Kouichi
Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title_full Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title_fullStr Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title_full_unstemmed Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title_short Does endoscopic ultrasound-guided fine needle biopsy using a Franseen needle really offer high diagnostic accuracy? A propensity-matched analysis
title_sort does endoscopic ultrasound-guided fine needle biopsy using a franseen needle really offer high diagnostic accuracy? a propensity-matched analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805192/
https://www.ncbi.nlm.nih.gov/pubmed/31673602
http://dx.doi.org/10.1055/a-0957-3005
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