Cargando…

Metabolic signature of obesity-associated insulin resistance and type 2 diabetes

BACKGROUND: Obesity is associated with an increased risk of insulin resistance and type 2 diabetes mellitus (T2DM). However, some obese individuals maintain their insulin sensitivity and exhibit a lower risk of associated comorbidities. The underlying metabolic pathways differentiating obese insulin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Sulaiti, Haya, Diboun, Ilhame, Agha, Maha V., Mohamed, Fatima F. S., Atkin, Stephen, Dömling, Alex S., Elrayess, Mohamed A., Mazloum, Nayef A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805293/ https://www.ncbi.nlm.nih.gov/pubmed/31640727 http://dx.doi.org/10.1186/s12967-019-2096-8

Ejemplares similares

Triglyceride profiling in adipose tissues from obese insulin sensitive, insulin resistant and type 2 diabetes mellitus individuals
por: Al-Sulaiti, Haya, et al.
Publicado: (2018)

Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance
por: Almuraikhy, Shamma, et al.
Publicado: (2016)

Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
por: Al-Muraikhy, Shamma, et al.
Publicado: (2021)

Metabolomic Profiling of Pregnancies With Polycystic Ovary Syndrome Identifies a Unique Metabolic Signature and Potential Predictive Biomarkers of Low Birth Weight
por: Diboun, Ilhame, et al.
Publicado: (2021)

Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery
por: Diboun, Ilhame, et al.
Publicado: (2020)

Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome
por: Moin, Abu Saleh Md, et al.
Publicado: (2021)

Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
por: AlMuraikhy, Shamma, et al.
Publicado: (2022)

The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals
por: Almuraikhy, Shamma, et al.
Publicado: (2023)

Combined metformin and insulin treatment reverses metabolically impaired omental adipogenesis and accumulation of 4-hydroxynonenal in obese diabetic patients
por: Jaganjac, Morana, et al.
Publicado: (2017)

Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity
por: Elrayess, Mohamed A., et al.
Publicado: (2022)

A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines
por: Al-Khelaifi, Fatima, et al.
Publicado: (2018)

Statistical methods and resources for biomarker discovery using metabolomics
por: Anwardeen, Najeha R., et al.
Publicado: (2023)

Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia
por: Mousa, Hanaa, et al.
Publicado: (2022)

Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance
por: Al-Khelaifi, Fatima, et al.
Publicado: (2019)

Author Correction: Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance
por: Al-Khelaifi, Fatima, et al.
Publicado: (2020)

Metabolomics profiling of xenobiotics in elite athletes: relevance to supplement consumption
por: Al-Khelaifi, Fatima, et al.
Publicado: (2018)

Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
por: Almuraikhy, Shamma, et al.
Publicado: (2023)

Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women
por: Ramanjaneya, Manjunath, et al.
Publicado: (2022)

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19
por: Moin, Abu Saleh Md, et al.
Publicado: (2021)

Age and Sport Intensity-Dependent Changes in Cytokines and Telomere Length in Elite Athletes
por: Sellami, Maha, et al.
Publicado: (2021)

From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance
por: Alser, Maha, et al.
Publicado: (2022)

Antioxidative Stress Metabolic Pathways in Moderately Active Individuals
por: Almuraikhy, Shamma, et al.
Publicado: (2023)

SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
por: Majeed, Yasser, et al.
Publicado: (2021)

Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
por: Madani, Aisha Y., et al.
Publicado: (2021)

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
por: Diboun, Ilhame, et al.
Publicado: (2022)

Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition
por: Diboun, Ilhame, et al.
Publicado: (2015)

Predictive Biomarkers of Intensive Care Unit and Mechanical Ventilation Duration in Critically-Ill Coronavirus Disease 2019 Patients
por: Taleb, Sara, et al.
Publicado: (2021)

Prevalence and Predictors of Insulin Resistance in Non-Obese Healthy Young Females in Qatar
por: Elrayess, Mohamed A., et al.
Publicado: (2020)

Hypoglycemia-induced changes in complement pathways in type 2 diabetes
por: Moin, Abu Saleh Md, et al.
Publicado: (2021)

Comparing Levels of Metabolic Predictors of Coronary Heart Disease between Healthy Lean and Overweight Females
por: Abu-El-Ruz, Rasha, et al.
Publicado: (2021)

Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar
por: Sohail, Muhammad U., et al.
Publicado: (2019)

High Endurance Elite Athletes Show Age-dependent Lower Levels of Circulating Complements Compared to Low/Moderate Endurance Elite Athletes
por: Al-Muraikhy, Shamma, et al.
Publicado: (2021)

Association of microRNAs With Embryo Development and Fertilization in Women Undergoing Subfertility Treatments: A Pilot Study
por: Butler, Alexandra E., et al.
Publicado: (2021)

Corrigendum: Association of microRNAs With Embryo Development and Fertilization in Women Undergoing Subfertility Treatments: A Pilot Study
por: Butler, Alexandra E., et al.
Publicado: (2022)

Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells
por: Alheidous, Sara, et al.
Publicado: (2022)

Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance
por: Al-Mansoori, Layla, et al.
Publicado: (2021)

Identification of Prognostic Metabolomic Biomarkers at the Interface of Mortality and Morbidity in Pre-Existing TB Cases Infected With SARS-CoV-2
por: Diboun, Ilhame, et al.
Publicado: (2022)

Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status
por: Diboun, Ilhame, et al.
Publicado: (2021)

Na(+)/H(+) Exchanger Isoform 1 Induced Cardiomyocyte Hypertrophy Involves Activation of p90 Ribosomal S6 Kinase
por: Jaballah, Maiy, et al.
Publicado: (2015)

SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition
por: Abdesselem, Houari, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ba52f3ifrtue4bpcrr99su2f05