A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target

BACKGROUND: Merkel cell carcinomas (MCCs) are rare, aggressive, therapeutically-challenging skin tumours that are increasing in incidence and have poor survival rates. The majority are caused by genomic Merkel cell polyomavirus (MCPyV) integration and MCPyV T-antigen expression. Recently, a potentia...

Descripción completa

Detalles Bibliográficos
Autores principales: Cappabianca, Lucia, Guadagni, Stefano, Maccarone, Rita, Sebastiano, Michela, Chiominto, Alessandro, Farina, Antonietta Rosella, Mackay, Andrew Reay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805356/
https://www.ncbi.nlm.nih.gov/pubmed/31640749
http://dx.doi.org/10.1186/s13046-019-1425-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805356/
https://www.ncbi.nlm.nih.gov/pubmed/31640749
http://dx.doi.org/10.1186/s13046-019-1425-3

Ejemplares similares