Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral variant FTD (bv...

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Detalles Bibliográficos
Autores principales: Lin, Li-Chun, Nana, Alissa L., Hepker, Mackenzie, Hwang, Ji-Hye Lee, Gaus, Stephanie E., Spina, Salvatore, Cosme, Celica G., Gan, Li, Grinberg, Lea T., Geschwind, Daniel H., Coppola, Giovanni, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805408/
https://www.ncbi.nlm.nih.gov/pubmed/31640778
http://dx.doi.org/10.1186/s40478-019-0809-0

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