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Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson’s disease

Aggregation of alpha-synuclein (α-SYN) is the pathological hallmark of several diseases named synucleinopathies, including Parkinson’s disease (PD), which is the most common neurodegenerative motor disorder. Alpha-SYN has been linked to synaptic function both in physiological and pathological condit...

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Detalles Bibliográficos
Autores principales: Torre-Muruzabal, Teresa, Devoght, Jens, Van den Haute, Chris, Brône, Bert, Van der Perren, Anke, Baekelandt, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805517/
https://www.ncbi.nlm.nih.gov/pubmed/31640762
http://dx.doi.org/10.1186/s40478-019-0814-3