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A cAbl-MRTF-A Feedback Loop Contributes to Hepatic Stellate Cell Activation
Trans-differentiation of quiescent hepatic stellate cells (HSC) to myofibroblasts is a hallmark event in liver fibrosis. Previous studies have led to the discovery that myocardin-related transcription factor A (MRTF-A) is a key regulator of HSC trans-differentiation or, activation. In the present st...
Autores principales: | Lu, Yunjie, Lv, Fangqiao, Kong, Ming, Chen, Xuyang, Duan, Yunfei, Chen, Xuemin, Sun, Donglin, Fang, Mingming, Xu, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805704/ https://www.ncbi.nlm.nih.gov/pubmed/31681772 http://dx.doi.org/10.3389/fcell.2019.00243 |
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