Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry

Native top-down mass spectrometry is a fast, robust biophysical technique that can provide molecular-scale information on the interaction between proteins or peptides and ligands, including metal cations. Here we have analyzed complexes of the full-length amyloid β (1-42) monomer with a range of (pa...

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Detalles Bibliográficos
Autores principales: Lermyte, Frederik, Everett, James, Lam, Yuko P. Y., Wootton, Christopher A., Brooks, Jake, Barrow, Mark P., Telling, Neil D., Sadler, Peter J., O’Connor, Peter B., Collingwood, Joanna F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805827/
https://www.ncbi.nlm.nih.gov/pubmed/31350722
http://dx.doi.org/10.1007/s13361-019-02283-7

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