Sub-nanomolar sensitive GZnP3 reveals TRPML1-mediated neuronal Zn(2+) signals

Although numerous fluorescent Zn(2+) sensors have been reported, it is unclear whether and how Zn(2+) can be released from the intracellular compartments into the cytosol due to a lack of probes that can detect physiological dynamics of cytosolic Zn(2+). Here, we create a genetically encoded sensor,...

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Detalles Bibliográficos
Autores principales: Minckley, Taylor F., Zhang, Chen, Fudge, Dylan H., Dischler, Anna M., LeJeune, Kate D., Xu, Haoxing, Qin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805855/
https://www.ncbi.nlm.nih.gov/pubmed/31641116
http://dx.doi.org/10.1038/s41467-019-12761-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805855/
https://www.ncbi.nlm.nih.gov/pubmed/31641116
http://dx.doi.org/10.1038/s41467-019-12761-x

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