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Sub-nanomolar sensitive GZnP3 reveals TRPML1-mediated neuronal Zn(2+) signals
Although numerous fluorescent Zn(2+) sensors have been reported, it is unclear whether and how Zn(2+) can be released from the intracellular compartments into the cytosol due to a lack of probes that can detect physiological dynamics of cytosolic Zn(2+). Here, we create a genetically encoded sensor,...
Autores principales: | Minckley, Taylor F., Zhang, Chen, Fudge, Dylan H., Dischler, Anna M., LeJeune, Kate D., Xu, Haoxing, Qin, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805855/ https://www.ncbi.nlm.nih.gov/pubmed/31641116 http://dx.doi.org/10.1038/s41467-019-12761-x |
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