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Maternal insulin resistance multigenerationally impairs synaptic plasticity and memory via gametic mechanisms

Metabolic diseases harm brain health and cognitive functions, but whether maternal metabolic unbalance may affect brain plasticity of next generations is still unclear. Here, we demonstrate that maternal high fat diet (HFD)-dependent insulin resistance multigenerationally impairs synaptic plasticity...

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Detalles Bibliográficos
Autores principales:	Fusco, Salvatore, Spinelli, Matteo, Cocco, Sara, Ripoli, Cristian, Mastrodonato, Alessia, Natale, Francesca, Rinaudo, Marco, Livrizzi, Giulia, Grassi, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805915/ https://www.ncbi.nlm.nih.gov/pubmed/31641124 http://dx.doi.org/10.1038/s41467-019-12793-3

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