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Classification of GABAergic interneurons by leading neuroscientists
There is currently no unique catalog of cortical GABAergic interneuron types. In 2013, we asked 48 leading neuroscientists to classify 320 interneurons by inspecting images of their morphology. That study was the first to quantify the degree of agreement among neuroscientists in morphology-based int...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805952/ https://www.ncbi.nlm.nih.gov/pubmed/31641131 http://dx.doi.org/10.1038/s41597-019-0246-8 |
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author | Mihaljević, Bojan Benavides-Piccione, Ruth Bielza, Concha Larrañaga, Pedro DeFelipe, Javier |
author_facet | Mihaljević, Bojan Benavides-Piccione, Ruth Bielza, Concha Larrañaga, Pedro DeFelipe, Javier |
author_sort | Mihaljević, Bojan |
collection | PubMed |
description | There is currently no unique catalog of cortical GABAergic interneuron types. In 2013, we asked 48 leading neuroscientists to classify 320 interneurons by inspecting images of their morphology. That study was the first to quantify the degree of agreement among neuroscientists in morphology-based interneuron classification, showing high agreement for the chandelier and Martinotti types, yet low agreement for most of the remaining types considered. Here we present the dataset containing the classification choices by the neuroscientists according to interneuron type as well as to five prominent morphological features. These data can be used as crisp or soft training labels for learning supervised machine learning interneuron classifiers, while further analyses can try to pinpoint anatomical characteristics that make an interneuron especially difficult or especially easy to classify. |
format | Online Article Text |
id | pubmed-6805952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-68059522019-10-30 Classification of GABAergic interneurons by leading neuroscientists Mihaljević, Bojan Benavides-Piccione, Ruth Bielza, Concha Larrañaga, Pedro DeFelipe, Javier Sci Data Data Descriptor There is currently no unique catalog of cortical GABAergic interneuron types. In 2013, we asked 48 leading neuroscientists to classify 320 interneurons by inspecting images of their morphology. That study was the first to quantify the degree of agreement among neuroscientists in morphology-based interneuron classification, showing high agreement for the chandelier and Martinotti types, yet low agreement for most of the remaining types considered. Here we present the dataset containing the classification choices by the neuroscientists according to interneuron type as well as to five prominent morphological features. These data can be used as crisp or soft training labels for learning supervised machine learning interneuron classifiers, while further analyses can try to pinpoint anatomical characteristics that make an interneuron especially difficult or especially easy to classify. Nature Publishing Group UK 2019-10-22 /pmc/articles/PMC6805952/ /pubmed/31641131 http://dx.doi.org/10.1038/s41597-019-0246-8 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files associated with this article. |
spellingShingle | Data Descriptor Mihaljević, Bojan Benavides-Piccione, Ruth Bielza, Concha Larrañaga, Pedro DeFelipe, Javier Classification of GABAergic interneurons by leading neuroscientists |
title | Classification of GABAergic interneurons by leading neuroscientists |
title_full | Classification of GABAergic interneurons by leading neuroscientists |
title_fullStr | Classification of GABAergic interneurons by leading neuroscientists |
title_full_unstemmed | Classification of GABAergic interneurons by leading neuroscientists |
title_short | Classification of GABAergic interneurons by leading neuroscientists |
title_sort | classification of gabaergic interneurons by leading neuroscientists |
topic | Data Descriptor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805952/ https://www.ncbi.nlm.nih.gov/pubmed/31641131 http://dx.doi.org/10.1038/s41597-019-0246-8 |
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