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WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells

Hypoxia/reoxygenation (H/R) treatment reportedly induces DNA damage response (DDR), including DNA double-strand break (DSB) repair and G2 arrest, resulting in reduction of clonogenic survival. Because WEE1 plays a key role in the G2/M checkpoint along with CHK1/2, we investigated the effect of WEE1...

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Detalles Bibliográficos
Autores principales:	Goto, Tatsuaki, Homma, Hisao, Kaida, Atsushi, Miura, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805980/ https://www.ncbi.nlm.nih.gov/pubmed/31347653 http://dx.doi.org/10.1093/jrr/rrz045

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