MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications

Efavirenz (EFV) and rifampicin (RMP) are widely prescribed in Africa for treatment of HIV/AIDS and tuberculosis epidemics. Exposure to medicines can alter drug metabolism, for example, through changes in expression of microRNAs. We report, in this study, novel observations on the ways in which EFV a...

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Detalles Bibliográficos
Autores principales: Swart, Marelize, Dandara, Collet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806364/
https://www.ncbi.nlm.nih.gov/pubmed/31526233
http://dx.doi.org/10.1089/omi.2019.0122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806364/
https://www.ncbi.nlm.nih.gov/pubmed/31526233
http://dx.doi.org/10.1089/omi.2019.0122

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